个人简介

  黄良刚，男，博士，讲师。1989年10月出生，江西上饶人。2020年6月于华南理工大学获得发酵工程专业博士学位。主要研究方向为通过基因编辑技术结合多组学研究完成微生物细胞工厂遗传改造，实现蛋白（药用蛋白、工业酶制剂）表达、代谢产物合成途径优化、天然产物定点激活等。参与了国家自然科学基金、广东省科技计划-粤港联合创新项目、广东省科技计划项目、广州市科技计划项目等国家级和省部级项目。目前发表研究论文5篇，申请发明专利1项。曾获得华南理工大学研究生学术节二等奖。

联系方式

Email：liangganghuang@zjut.edu.cn

代表性论文论著

1. Lianggang Huang, Hongzhi Dong, Junwei Zheng, Bin Wang, Li Pan*. Highly efficient single base editing in Aspergillus niger with CRISPR/Cas9 cytidine deaminase fusion. Microbiological research, 2019, 223-225: 44-50.

2. Lianggang Huang, Liangbo Dong, Bin Wang, Li Pan*. The transcription factor PrtT and its target protease profiles in Aspergillus niger are negatively regulated by carbon sources. Biotechnology letters, 2020, 42(4), 613-624.

3. Lianggang Huang, Xuejie Li, Liangbo Dong, Bin Wang*, Li Pan*. Profiling of chromatin accessibility across Aspergillus species and identification of transcription factor binding sites in Aspergillus genome using improved ATAC-Seq technique for filamentous fungi. BMC Biology, DOI：https://doi.org/10.1101/857284. (In rivision)

4. Yuling Liao, Lianggang Huang, Bin Wang, Feng Zhou, Li Pan*. The global transcriptional landscape of Bacillus amyloliquefaciens XH7 and high-throughput screening of strong promoters based on RNA-seq data. Gene, 2015, 571(2): 252-262.

5. Liangbo Dong, Xiaotong Lin, Dou Yu, Lianggang Huang, Bin Wang, Li Pan*. High-level expression of highly active and thermostable trehalase from Myceliophthora thermophila in Aspergillus niger by using the CRISPR-Cas9 tool and its application in ethanol fermentation. Journal of Industrial Microbiology & Biotechnology, 2019:1-12.

发明专利

1. 潘力，黄良刚，董宏智，郑俊威，王斌. 一种能实现碱基突变的pFC330-BEC质粒及其应用。授权国：中国，公开号：CN201910225983.1，公开日：2019年07月02日。